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Dr.聽Seuntjens' research focuses on the applications of physics in medicine and biology. He has聽been primarily involved with techniques to optimize the efficacy of radiation therapy by making the determination and planning of the dose delivered in radiation therapy more accurate. To this end he has developed special Monte Carlo simulation techniques and detection techniques. These Monte Carlo techniques are now routinely used in clinical practice.聽A second area of interest is the development of new radiation therapy treatment techniques. These include Modulated Electron Radiation Therapy (MERT) as well as intraoperative radiation therapy techniques (IORT). In addition,聽he has聽also worked on microscopic Monte Carlo computational methods to better understand the mechanistic effect of radiation on cellular response.