黑料不打烊

A new 'atlas' of genetic influences on osteoporosis

A ground-breaking new study led by researchers from the Lady Davis Institute (LDI) at the Jewish General Hospital (JGH) has succeeded in compiling an atlas of genetic factors associated with estimated bone mineral density (BMD), one of the most clinically relevant factors in diagnosing osteoporosis. The paper, published in Nature Genetics, identifies 518 genome-wide loci, of which 301 are newly discovered, that explain 20% of the genetic variance associated with osteoporosis.

Suboptimal, inconsistent treatment for anaphylaxis due to unknown cause

A new Canadian study, led by a team at the Research Institute of the 黑料不打烊 University Health Centre (RI-MUHC), is shedding light on anaphylaxis due to an unknown trigger (AUT)鈥攁n unpredictable and potentially fatal allergic reaction, about which surprisingly little is known.

The importance of 鈥榚dge populations鈥� to biodiversity

More than two-thirds of Canada鈥檚 biodiversity is made up of species that occur within the country鈥檚 borders only at the very northern edge of their range. Biologists have long debated how much effort should be dedicated to conserving these 鈥渆dge populations.鈥� One argument in their favour is that they may be especially well suited to lead northward range shifts for their species as the climate warms.

Wound care revolution: Put away your rulers and reach for your phone

Monitoring a wound is critical, especially in diabetic patients, whose lack of sensation due to nerve damage can lead to infection of a lesion and, ultimately, amputation. New research from the 黑料不打烊 University Health Centre (MUHC) and 黑料不打烊 University shows that the use of a new app, called Swift Skin and Wound鈩�, which accurately measures and charts the progression of skin wounds, could potentially have a significant impact on clinical management and patient outcomes.

How does cancer spread?

How does cancer spread? While studying human brain tumour cells, a team of scientists at the Research Institute of the 黑料不打烊 University Health Centre (RI-MUHC) found some answers to this crucial, yet so far unanswered question. They looked at a gene called EGFRvIII, which is present in patients with glioblastoma 鈥� a highly aggressive form of brain cancer that spreads quickly and that is difficult to treat.

鈥嬧�嬧�嬧�嬧�嬧�嬧�婸redicting the transmission of rare, genetically based diseases

There are only 25 people in the whole of Quebec at the moment who have a rare recessive genetic disease called chronic atrial and intestinal dysrhythmia (CAID). It is a serious disease that affects both heart rate and intestinal movements. A 黑料不打烊-led research team has been able to trace the gene mutations underlying the disease back to two European founding families who arrived in the province in the 17th century.

Another Medical Cold Case Cracked by the MUHC鈥檚 鈥楧r. House鈥�

A team from the Research Institute of the 黑料不打烊 University Health Centre (RI-MUHC) led by Dr. Donald Vinh, the RI鈥檚 so-called 鈥淒r. House鈥� because of his research into rare diseases, has discovered a new human disease and the gene responsible for it, paving the way for the proper diagnosis of patients globally and the development of new therapies. Their findings are published in the Journal of Experimental Medicine.

Are scientists studying the wrong kind of mice?

Mice represent well over half of the non-human subjects of biomedical research, and the vast majority of those mice are inbred. Formed by generation after generation of mating between brothers and sisters, inbred mice are genetically identical to each other, like twins or clones. Inbreeding is well known to reduce health and vigor across species; this biological fact is the reason that incest is a universal taboo.

Can a smart app encourage HIV-self testing in Canada?

HIV self-testing strategies have been recommended by the World Health Organization (WHO) since 2016, as they empower people to find out HIV their status at their convenience. However, home-based testing kits have yet to be approved for sale in Canada.

When a city feels good, people take more risks

What makes people take risks? Not stunt women or formula 1 drivers. Just ordinary people like you and me. Research published this week in PLOS ONE suggests that unexpected improvements in everyday life (sunshine after many days of rain or a win by a local sports team) are correlated with a change in a city鈥檚 mood and an increased likelihood that it鈥檚 citizens will do risky things like gamble.

Social media and city mood