YCharOS antibody characterization platform addresses the 鈥渞eproducibility crisis鈥� in research

An innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.

YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.

YCharOS antibody characterization platform addresses the 鈥渞eproducibility crisis鈥� in research

An innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.

YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.

96 Global Health NOW: Malaria in Children Surges in South Sudan; Seeking Suicide Intervention in Japan; and America鈥檚 Covid-19 Hangover November 12, 2024 Malaria in Children Surges in South Sudan
An upsurge in malaria cases in South Sudan, fueled by recent floods, is overwhelming the country鈥檚 health system, .

• Pediatric patients with severe malaria have swamped a M茅decins Sans Fronti猫res-supported hospital in Northern Bahr el Ghazal state, , forcing doctors to treat some patients in halls.


• 400 children with severe malaria are admitted weekly鈥�2X last year鈥檚 numbers.

Another Impact: Oil-Contaminated Water

Years of unprecedented flooding have left large swaths of South Sudan鈥檚 Unity State submerged, allowing pollution from mismanaged oil production facilities to seep into drinking water sources鈥攃ausing digestive illnesses and birth defects, .
 
No recourse: Reliance on the oil industry means little has been done to hold companies accountable, advocates say鈥攚ith one former oil engineer describing the spreading oil as a 鈥渟ilent killer.鈥� DATA POINT The Latest One-Liners
Refugees and asylum seekers are nearly 3X as likely to be colonized or infected with drug-resistant bacteria as the host-country population, that explored case studies in nine current humanitarian settings.

Dengue death rates are 2X higher for women (1.86%) than men (0.61%) in Chattogram, Bangladesh, this year; doctors say delayed hospitalization, anemia, and low blood pressure鈥攁ll more common among women鈥攅xplain the disparity.

The American Stroke Association鈥檚 on stroke prevention鈥攖he first in 10 years鈥攔ecommend that doctors consider a new class of drugs that can drastically reduce weight, and screen for non-medical risk factors like economic stability and racism.

Online e-cigarette retailers are failing to comply with restrictions on sales for minors, including regulations on age verification, shipping methods, and flavor restrictions ; delivery services only scanned IDs for 1% of buyers. MENTAL HEALTH Seeking Suicide Intervention in Japan
Advocates in Japan are calling for a greater focus on youth mental health after suicides among schoolchildren in the country remained 鈥渁larmingly high鈥� in 2023.

• 513 deaths were reported in Japan last year鈥攎arking the second consecutive year above 500, per Japan鈥檚 Ministry of Health, and a sharp increase from 300 in 2010. 

Contributing factors: Family economic stress, bullying, school pressures, reduced in-person socialization, and disillusion about the future are all contributing to the crisis, researchers said.

• 鈥淥ne of the biggest problems among young people today is that they find it difficult to be optimistic about their future,鈥� said Izumi Tsuji, a sociologist at Chuo University and member of the Japan Youth Study Group.

GLOBAL HEALTH VOICES ALCOHOL America鈥檚 Covid-19 Hangover
Drinking in the U.S. increased sharply during the pandemic and still hasn鈥檛 returned to pre-COVID-19 levels, .

• Americans who reported drinking heavily increased to 6.29% in 2022, up from 5.1% in 2018.


• 69.3% said they had consumed alcohol in the past year, up from 66.34% in 2018.


• 6.45% of women reported having drunk heavily, while the men鈥檚 reported rate was 6.12%.

The Quote: 鈥淧eople assumed this [drinking] was caused by acute stress, like what we saw with 9/11 and Katrina, and typically it goes back to normal after these stressful events are over,鈥� said principal investigator Brian P. Lee. 鈥淏ut that鈥檚 not what we鈥檙e seeing.鈥�

OPPORTUNITY QUICK HITS Rwanda discharges last patient of Marburg virus disease: WHO 鈥� 

Paxlovid cuts COVID hospitalization, death risk and speeds symptom relief, studies find 鈥�

US FDA lifts clinical hold on Novavax's combo COVID-flu shot 鈥�

Mpox Cases Plateau in Congo's Epicenter But Rise in Other Countries 鈥�

'More mortality, more illness': Global health community braces for impact of U.S. election 鈥�

No Pandemic Agreement By December As Negotiators Need 'More Time' 鈥�

More young people are surviving cancer. Then they face a life altered by it 鈥�

Easy-fit prosthetics offer hope to thousands of Gaza amputees 鈥� Issue No. 2813
Global Health NOW is an initiative of Johns Hopkins Bloomberg School of Public Health.

Contributors include Brian W. Simpson, MPH, Dayna Kerecman Myers, Annalies Winny, Morgan Coulson, Kate Belz, Melissa Hartman, Jackie Powder, Aliza Rosen, and Rin Swann. Write us: dkerecm1@jhu.edu, like us on and follow us on Instagram and X .

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