/channels/taxonomy/term/18151/all en /channels/channels/news/how-turn-specific-genes-and-334623 <p>Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not “turning on” and “turning off” as they should. By using new CRISPR/Cas9 genome editing technology, in a recent paper in <a href="https://www.nature.com/articles/s41467-021-25991-9/metrics"><i>Nature Communications</i></a><i>, </i>���ϲ����� University researchers have described a new technique that scientists across the world can potentially use to explore novel ways of treating diseases associated with dysregulation in DNA methylation.</p> Tue, 09 Nov 2021 15:19:08 +0000 webfull 174578 at /channels /channels/channels/news/five-mcgill-teams-awarded-funding-new-genomic-integration-program-331618 <p>Today Genome Quebec announced the results of its Genomic Integration Program, Human Health Stream competition. Five ���ϲ����� teams from a diverse array of fields were awarded funds, totaling nearly $1 million. One of the defining features of this program is the requirement that institutional applicants must also have an external non-academic partner, thus supporting program goals of stimulating the Quebec economy and encouraging the use of genomic technologies in the Quebec healthcare system.</p> Mon, 21 Jun 2021 17:24:00 +0000 webfull 171241 at /channels /channels/channels/news/experts-fda-approves-much-debated-alzheimers-drug-panned-experts-331414 <p>U.S. government health officials approved the first new drug for Alzheimer's disease in nearly 20 years, disregarding warnings from independent advisers that the much-debated treatment hasn't been shown to help slow the brain-destroying disease. The Food and Drug Administration (FDA) said it granted approval to the drug from Biogen based on results that seemed “reasonably likely” to benefit Alzheimer's patients. (<a href="https://www.ctvnews.ca/health/fda-approves-much-debated-alzheimer-s-drug-panned-by-experts-1.5459470" target="_blank">CTV News</a>)</p> Thu, 10 Jun 2021 14:35:58 +0000 webfull 171038 at /channels /channels/channels/news/molecular-alterations-neuronal-trophic-regulation-alzheimers-pathology-begin-decades-detectable-323532 <p style="text-align:center"><strong>Findings could lead to development of pre-clinical stage therapeutics</strong></p> <p><em>By Jason Clement</em></p> <p>For decades researchers have known that Alzheimer’s disease (AD) causes the atrophy of a system of neurons and synapses highly involved in memory, learning and attention, which is highly dependent on a molecule known as nerve growth factor (NGF). The disease causes dysregulation of NGF’s metabolism, leading to the loss of the synapses and neurons that depend on it, akin to plants being deprived of light.</p> Thu, 06 Aug 2020 20:10:01 +0000 webfull 162293 at /channels /channels/channels/news/brain-signaling-proteins-hit-road-running-296646 <p align="center"><strong>New study of brain neurotransmitter receptor has implications for drug discovery</strong></p> <p>Surprisingly complex movements in an important neurotransmitter receptor may help explain the brain’s unpredictable response to drugs, according to a new study. New research from an international team, published this week in the journal <i>Neuron</i>, has revealed that the resting state of signaling proteins are much more dynamic than previously thought.</p> Tue, 30 Apr 2019 18:41:00 +0000 webfull 148777 at /channels /channels/channels/news/dr-claudio-cuello-elected-fellow-british-academy-medical-sciences-287119 <p>Dr. Claudio Cuello, Professor and inaugural Charles E. Frosst/Merck endowed Chair in Pharmacology at ���ϲ����� University’s Faculty of Medicine is among a group of 48 leading biomedical and health scientists whose work is being recognized with election to the prestigious British Academy of Medical Sciences, announced on May 10.  The new Fellows have been elected for their outstanding contributions to biomedical and health science, leading research discoveries, and translating developments into benefits for patients and the wider society.</p> Thu, 10 May 2018 14:43:21 +0000 webfull 137916 at /channels